Tissue Microarray Kit
Tissue microarrays are paraffin blocks produced by extracting cylindrical tissue cores from different paraffin donor blocks and re-embedding these into a single recipient (microarray) block at defined array coordinates. Using this technique, multiple tissue samples can be arrayed into a single paraffin block. The use of tissue microarrays in combination with special applications like immunohistochemistry, immunofluorescence and fluorescent in-situ hybridization etc.. has been a preferred method to study and validate cancer biomarkers, drug discovery, product quality control in various diseased patient cohorts. The possibility to assemble a large number of representative diseased samples from a defined patient cohort that also has a corresponding clinical database, provides a powerful resource to study how different expressions and patterns correlate with different clinical parameters. Since patient samples are assembled into the same block, sections can be stained with the same protocol to avoid experimental variability and technical errors. Clinical patient cohorts and corresponding tissue microarray sets have been used to study diagnostic, prognostic and treatment predictive cancer biomarkers, molecular pathology based applications in most tissue related studies. PathnSitu offers a wide range of tissue micro array molds of multiple core sizes of 2mm, 3mm, 4mm and 5mm with various number of cores starting from 5 to 59.
Tissue microarrays are paraffin blocks produced by extracting cylindrical tissue cores from different paraffin donor blocks and re-embedding these into a single recipient (microarray) block at defined array coordinates. Using this technique, multiple tissue samples can be arrayed into a single paraffin block. The use of tissue microarrays in combination with special applications like immunohistochemistry, immunofluorescence and fluorescent in-situ hybridization etc.. has been a preferred method to study and validate cancer biomarkers, drug discovery, product quality control in various diseased patient cohorts. The possibility to assemble a large number of representative diseased samples from a defined patient cohort that also has a corresponding clinical database, provides a powerful resource to study how different expressions and patterns correlate with different clinical parameters. Since patient samples are assembled into the same block, sections can be stained with the same protocol to avoid experimental variability and technical errors. Clinical patient cohorts and corresponding tissue microarray sets have been used to study diagnostic, prognostic and treatment predictive cancer biomarkers, molecular pathology based applications in most tissue related studies. PathnSitu offers a wide range of tissue micro array molds of multiple core sizes of 2mm, 3mm, 4mm and 5mm with various number of cores starting from 5 to 59.
