PD-1-EP239

Programmed death-1 (PD-1), also known as CD279, is a receptor for PDL1 and PDL2. PD1 plays a crucial role in regulating peripheral tolerance and tumor immunity. PD-1 is expressed mainly on a subset of activated T-cells, B-cells and myeloid cells. Increased expression of PD-1 has been reported to be associated with poor prognosis in hepatocellular carcinoma (HCC) and renal cell carcinoma. PD1 positivity has been found in angioimmunoblastic lymphoma, but not other subtypes of T cell and B cell non-Hodgkin lymphoma and classic Hodgkin lymphoma. PD-1 is a useful marker for angioimmunoblastic lymphoma.

• Source
  Rabbit Monoclonal
• Clone
  EP239
• Class
  IVD
• Isotype
  Rabbit IgG
• Tested Reactivity
  Human, FFPE
• Localization
  Cytoplasm & Membrane
• Positive Control
  Tonsil, High risk RCC

• Catalog
  Pack Size
• PR198-3ml
  3 ml(RTU)
• PR198-6ml
  6 ml(RTU)
• CR198-0.1ml
  0.1 ml(Conc.)
• CR198-0.5ml
  0.5 ml(Conc.)
• HAR198-3ml
  3 ml(RTU)
• HAR198-6ml
  6 ml(RTU)
• CR198 - 1ml
  1ml ( Conc. )