p53-BP-53-12

p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair.p53 is overexpressed in over 50% of human cancers. Positive staining of p53 detected by immunohistochemistry has been observed in colon cancer, breast cancer and ovary cancer.

• Source
  Mouse Monoclonal
• Clone
  BP-53-12
• Class
  IVD
• Isotype
  Mouse IgG2a
• Tested Reactivity
  Human, FFPE
• Localization
  Nucleus
• Positive Control
  Ovarian Ca, Breast Ca, Colon Ca

• Catalog
  Pack Size
• PM101-3ml
  3 ml(RTU)
• PM101-6ml
  6 ml(RTU)
• CM101-0.1ml
  0.1 ml(Conc.)
• CM101-0.5ml
  0.5 ml(Conc.)
• HAM101-3ml
  3 ml(RTU)
• HAM101-6ml
  6 ml(RTU)
• CM101 - 1ml
  1ml ( Conc. )

1. Immunohistochemical Expression of Ki-67, P53 and HER2/neu in Meningiomas
   https://pdfs.semanticscholar.org/189d/f8c9a40f1233b7c460d1cd35368e1029a711.pdf
   
   
2. Chemopreventive Synergism between Green Tea Extract and Curcumin in Patients with Potentially Malignant Oral Disorders: A Double-blind, Randomized Preliminary Study
   https://www.researchgate.net/profile/Nandish_V_S/publication/341768366_Chemopreventive_Synergism_between_Green_Tea_Extract_and_Curcumin_in_Patients_with_Potentially_Malignant_Oral_Disorders_A_Double-blind_Randomized_Preliminary_Study/links/5eddd32092851c9c5e8fa087/Chemopreventive-Synergism-between-Green-Tea-Extract-and-Curcumin-in-Patients-with-Potentially-Malignant-Oral-Disorders-A-Double-blind-Randomized-Preliminary-Study.pdf