GEMININ-EP355

Geminin is a regulator of DNA Replication . It interacts with DNA replication initiation factor CDT1P to inhibit the initiation of DNA replication .Geminin is absent during G1 phase, accumulates during S, G2 and M phases, and disappears at the metaphase-anaphase transition. Geminin is expressed in proliferating cells. Over expression of Geminin has been found in tumors and the expression of Geminin in Lymphomas and Carcinomas of the breast, colon and stomach is Correlated with cell proliferation as measured by Ki-67 staining.

• Source
  Rabbit Monoclonal
• Clone
  EP355
• Class
  IVD
• Isotype
  Rabbit IgG1
• Tested Reactivity
  Human, FFPE
• Localization
  Nuclear
• Positive Control
  Tonsil, Normal Thymus, Anaplastic large cell Lymphoma

• Catalog
  Pack Size
• PR272-3ml
  3ml(RTU)
• PR272-6ml
  6ml(RTU)
• CR272 - 0.5ml
  0.5ml ( Conc. )
• CR272 - 0.1ml
  0.1ml ( Conc. )
• CR272 - 1ml
  1ml ( Conc. )