Papillary Thyroid Ca stained with Anti-Galectin3
Galectin-3 (GAL3), encoded by LGALS3, is a structurally unique member of the ancient galectin family of β-galactoside-binding lectins. In addition to a carbohydrate binding domain, GAL3 can form oligomers through a proline and glycine-rich Nterminus. GAL3 is involved in many biological processes, such as cell growth, cell differentiation, cell-cell and cell-matrix adhesion interactions, angiogenesis, and apoptosis. GAL3 can be found in many different types of cells and tissues. It is located in the nucleus. cytoplasm, and outside the cell via the non-classical pathway. GAL3 has also been shown to be involved with cancer, inflammation, and heart failure-where it is associated with processes such as inflammation, myofibroblast proliferation, fibrogenesis, and tissue repair. Due to the wide range of mechanisms surrounding GAL3 and cancer, the GAL3 antibody is a promising approach for the development of therapeutic agents for cancer treatment
Galectin-3 (GAL3), encoded by LGALS3, is a structurally unique member of the ancient galectin family of β-galactoside-binding lectins. In addition to a carbohydrate binding domain, GAL3 can form oligomers through a proline and glycine-rich Nterminus. GAL3 is involved in many biological processes, such as cell growth, cell differentiation, cell-cell and cell-matrix adhesion interactions, angiogenesis, and apoptosis. GAL3 can be found in many different types of cells and tissues. It is located in the nucleus. cytoplasm, and outside the cell via the non-classical pathway. GAL3 has also been shown to be involved with cancer, inflammation, and heart failure-where it is associated with processes such as inflammation, myofibroblast proliferation, fibrogenesis, and tissue repair. Due to the wide range of mechanisms surrounding GAL3 and cancer, the GAL3 antibody is a promising approach for the development of therapeutic agents for cancer treatment
