CD15-MMA

CD15-MMA

CD15 is a complex cluster of cell surface glycoproteins and glycolipids with a common trisaccharide structure, 3-fucosyl-N-acetyllactosamine (3-FL), also referred to as Lewis X (LeX) antigen. This antigen is involved in neutrophil functions such as, cell-cell interactions, phagocytosis, stimulation of degranulation and respiratory burst. The CD15 is expressed in Reed-Sternberg cells, myeloid cells as well as epithelial cells. CD15 antibody has been used as an immunohistochemical marker to identify Reed-Sternberg cells (RSC) in Classical Hodgkin Lymphoma (CHL).

  • Description
  • Specifications
  • Ordering Information

CD15 is a complex cluster of cell surface glycoproteins and glycolipids with a common trisaccharide structure, 3-fucosyl-N-acetyllactosamine (3-FL), also referred to as Lewis X (LeX) antigen. This antigen is involved in neutrophil functions such as, cell-cell interactions, phagocytosis, stimulation of degranulation and respiratory burst. The CD15 is expressed in Reed-Sternberg cells, myeloid cells as well as epithelial cells. CD15 antibody has been used as an immunohistochemical marker to identify Reed-Sternberg cells (RSC) in Classical Hodgkin Lymphoma (CHL).

  • Source
    Mouse Monoclonal
  • Clone
    MMA
  • Isotype
    Mouse, IgM
  • Tested Reactivity
    Human, FFPE
  • Localization
    Membrane & Cytoplasm
  • Positive Control
    Hodgkins Lymphoma
  • Catalog
    Pack Size
  • PM379
    3 ml(RTU)
  • PM379
    6ml (RTU)
  • CM379
    0.1 ml(Conc.)
  • CM379
    0.5 ml(Conc.)
  • CM379
    1 ml(Conc.)
  • HAM379
    3ml (RTU)
  • HAM379
    6ml (RTU)