GIST stained with Anti-CD117 / c- kit
This antibody reacts with human oncoprotein c-kit (CD117). The protooncogene ckit encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117), which is closely related to the family of platelet derived growth factor receptors. cKIT is involved in hematopoiesis, gametogenesis and melanogenesis. This antigen is expressed in the normal breast epithelium, melanocytes, mast cells and glia. This antibody is recommended to identify oncoprotein expression c-kit in a variety of normal and neoplastic tissues, including gastrointestinal stromal tumors (GIST). It is also expressed in testicular seminoma, small cell carcinomas of the lung, breast carcinomas, glioblastomas, and melanomas.
This antibody reacts with human oncoprotein c-kit (CD117). The protooncogene ckit encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117), which is closely related to the family of platelet derived growth factor receptors. cKIT is involved in hematopoiesis, gametogenesis and melanogenesis. This antigen is expressed in the normal breast epithelium, melanocytes, mast cells and glia. This antibody is recommended to identify oncoprotein expression c-kit in a variety of normal and neoplastic tissues, including gastrointestinal stromal tumors (GIST). It is also expressed in testicular seminoma, small cell carcinomas of the lung, breast carcinomas, glioblastomas, and melanomas.
