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Tonsil stained with anti-HISTONE H3 PHOSPHO(pT3)

HISTONE H3 PHOSPHO(pT3)-EP233

Histone H3 is a core histone protein, which complexes with the other histones to form the major constituents of chromatin in eukaryotic cells. In mammalian cells, phosphorylation of Threonine 3 residue in histone H3 reaches a maximum for condensation during mitosis. Phosphorylation of histone H3 (pHH3) occurs only during late G2 phase and mitosis. pHH3 is a marker for mitoses in various types of tumors. It is particularly useful in identifying mitotic figures in tumors with dense cellularity, limited mitotic activity, and/or abundant apoptotic, pyknotic or distorted nuclei. 

Specifications

  • Source
    Rabbit Monoclonal
  • Clone
    EP233
  • Class
    IVD
  • Isotype
    Rabbit IgG
  • Tested Reactivity
    Human,FFPE
  • Localization
    Nuclear
  • Positive Control
    Tonsil, Breast Ca

Ordering Information

  • Catalog
    Pack Size
  • PR237-3ml
    3 ml(RTU)
  • PR237-6ml
    6 ml(RTU)
  • HAR237-3ml
    3 ml(RTU)
  • HAR237-6ml
    6 ml(RTU)