Endometrial Benign Epithelium stained with Anti-Glut1
Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designed as Glut-1 to Glut-12. Glut-1, also known as SCL2A1, is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon , breast, cervical, lung, bladder, and mesothelioma, Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma(positive) from reactive mesothelium(negative).
Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designed as Glut-1 to Glut-12. Glut-1, also known as SCL2A1, is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon , breast, cervical, lung, bladder, and mesothelioma, Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma(positive) from reactive mesothelium(negative).
