Spleen stained with Anti-CD57
The CD57 glycoprotein, also known as HNK-1,has a molecular weight of 110 kD. It is found on a subset of mononuclear cells with natural killer activity and on neuroectodermal cells expressing myelin-associated glycoprotein. Many cells which co-express CD57 and CD8 proteins are a subset of suppressor/cytotoxic T cells. These cells play a role in the rejection of grafts in acute graft versus host diseases. The CD57 molecule is not expressed on erythrocytes or platelets
The CD57 glycoprotein, also known as HNK-1,has a molecular weight of 110 kD. It is found on a subset of mononuclear cells with natural killer activity and on neuroectodermal cells expressing myelin-associated glycoprotein. Many cells which co-express CD57 and CD8 proteins are a subset of suppressor/cytotoxic T cells. These cells play a role in the rejection of grafts in acute graft versus host diseases. The CD57 molecule is not expressed on erythrocytes or platelets
