GIST stained with Anti-CD117 c-Kit___
CD117(c-kit) is expressed on hematopoietic stem/progenitor cells, master cells, cajal cells, mammalian ductal epithelia, melanocytes, and basal cells of skin. The antibody is a useful tool for the identification of cancers expressing c-kit, e.g. small cell lung carcinoma(SLCL), mast cell diseases, Ewing sarcoma, and may aid in the differentiation between gastrointestinal stromal tumors(GISTs) and other intra-abdominal mesenchymal tumors along with other markers, e.g. CD34 and S-100.
CD117(c-kit) is expressed on hematopoietic stem/progenitor cells, master cells, cajal cells, mammalian ductal epithelia, melanocytes, and basal cells of skin. The antibody is a useful tool for the identification of cancers expressing c-kit, e.g. small cell lung carcinoma(SLCL), mast cell diseases, Ewing sarcoma, and may aid in the differentiation between gastrointestinal stromal tumors(GISTs) and other intra-abdominal mesenchymal tumors along with other markers, e.g. CD34 and S-100.
