Small Intestine stained with Anti-ACE2
.jpg "Normal testis stained with Anti-ACE2 (2)")
 stained with Anti-ACE2.jpg "Skin (neg) stained with Anti-ACE2")
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity. Acts as a receptor for SARS coronavirus/SARS-CoV. Acts as a receptor for Human coronavirus NL63/HCoV-NL63. ACE2 is also known as Angiotensin Converting Enzyme 2, ACEH, Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2, Angiotensin-Converting Enzyme-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, Angiotensin I Converting Enzyme 2, Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Metalloprotease MPROT15, Peptidyl-Dipeptidase A, EC 3.4.17.23, EC 3.4.17, EC 3.4.17.
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity. Acts as a receptor for SARS coronavirus/SARS-CoV. Acts as a receptor for Human coronavirus NL63/HCoV-NL63. ACE2 is also known as Angiotensin Converting Enzyme 2, ACEH, Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2, Angiotensin-Converting Enzyme-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, Angiotensin I Converting Enzyme 2, Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Metalloprotease MPROT15, Peptidyl-Dipeptidase A, EC 3.4.17.23, EC 3.4.17, EC 3.4.17.
