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GIST stained with anti-CD117(c-Kit)

c-Kit/CD117 – EP10

Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1.Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K.  c-Kit/CD117 is a marker for Mast cell and gastrointestinal stromal tumor.

Specifications

  • Source
    Rabbit Monoclonal
  • Clone
    EP10
  • Class
    IVD
  • Isotype
    Rabbit IgG
  • Tested Reactivity
    Human, FFPE
  • Localization
    Membranous, Cytoplasmic
  • Positive Control
    Gastrointestinal stromal tumor

Ordering Information

  • Catalog
    Pack Size
  • PR033-3ml
    3 ml(RTU)
  • PR033-6ml
    6 ml(RTU)
  • CR033-0.1ml
    0.1 ml(Conc.)
  • CR033-0.5ml
    0.5 ml(Conc.)
  • HAR033-3ml
    3 ml(RTU)
  • HAR033-6ml
    6 ml(RTU)