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Tonsil stained with anti-CD7

CD7-EP132

CD7 is a single-pass type 1 transmembrane protein that is a member of the immunoglobulin superfamily. It plays an essential role in T-cell interactions and also in T-cell/B-cell interactions during early lymphoid development. CD7 is expressed on thymocytes, T- and natural killer cells, and progenitors of lymphoid and myeloid cells. It is also expressed on T-cell Acute Lymphoblastic Leukemia/Lymphoma, Acute Myelogenous Leukemia, and Chronic Myelogenous Leukemia. CD7 antibody is the most sensitive and specific T-cell deletion marker. Loss of CD7 expression by neoplastic lymphocytes is considered a distinguishing characteristic of mycosis fungoides (MF) and cutaneous T-cell lymphoma.

Specifications

  • Source
    Rabbit Monoclonal
  • Clone
    EP132
  • Class
    IVD
  • Isotype
    Rabbit IgG
  • Tested Reactivity
    Human, FFPE
  • Localization
    Membranous
  • Positive Control
    Tonsil, Acute Lymphoblastic Leukemia

Ordering Information

  • Catalog
    Pack Size
  • PR015-3ml
    3 ml(RTU)
  • PR015-6ml
    6 ml(RTU)
  • CR015-0.1ml
    0.1 ml(Conc.)
  • CR015-0.5ml
    0.5 ml(Conc.)
  • HAR015-3ml
    3 ml(RTU)
  • HAR015-6ml
    6 ml(RTU)