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Hepatocellular Ca stained with anti-Arginase 1

Arginase 1-ARG1/1125+ARG1/1126

Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Specifications

  • Source
    Mouse Monoclonal
  • Clone
    ARG1/1125+ARG1/1126
  • Class
    IVD
  • Isotype
    Mouse IgG
  • Tested Reactivity
    Human,FFPE
  • Localization
    Cytoplasm
  • Positive Control
    Hepatocellular Ca

Ordering Information

  • Catalog
    Pack Size
  • PM230-3ml
    3 ml(RTU)
  • PM230-6ml
    6 ml(RTU)
  • CM230-0.1ml
    0.1 ml(Conc.)
  • CM230-0.5ml
    0.5 ml(Conc.)
  • HAM230-3ml
    3 ml(RTU)
  • HAM230-6ml
    6 ml(RTU)