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Tonsil stained with anti-Ki-67

Ki-67-MIB-1

The Ki-67 protein is a nuclear protein doublet, 345-395 kDa, playing a pivotal role in maintaining cell proliferation. In diagnostic histopathology and cell biology, the antibody has proven valuable for the demonstration of the Ki-67 antigen in normal and neoplastic cells, for example in soft-tissue sarcoma, prostatic adenocarcinoma, and breast carcinoma. The Ki-67 has been confirmed as a very powerful single prognostic factor for overall survival, with highly proliferative cases showing a much poorer outcome than tumors with low proliferation. In breast cancer, the proliferative index measured by Ki-67 immunoreactivity has both prognostic and predictive value.

Specifications

  • Source
    Mouse Monoclonal
  • Clone
    MIB-1
  • Class
    IVD
  • Isotype
    IgG1, kappa
  • Tested Reactivity
    Human,FFPE
  • Localization
    Nuclear
  • Positive Control
    Tonsil, Breast Ca

Ordering Information

  • Catalog
    Pack Size
  • PM210-3ml
    3 ml(RTU)
  • PM210-6ml
    6 ml(RTU)
  • CM210-0.1ml
    0.1 ml(Conc.)
  • CM210-0.5ml
    0.5 ml(Conc.)
  • HAM210-3ml
    3 ml(RTU)
  • HAM210-6ml
    6 ml(RTU)