Close
Tonsil stained with anti-PD1

PD1-PDCD1/922

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Specifications

  • Source
    Mouse Monoclonal
  • Clone
    PDCD1/922
  • Class
    IVD
  • Isotype
    Mouse IgG1, kappa
  • Tested Reactivity
    Human,FFPE
  • Localization
    Cell Surface, Cytoplasm
  • Positive Control
    Tonsil

Ordering Information

  • Catalog
    Pack Size
  • PM208-3ml
    3 ml(RTU)
  • PM208-6ml
    6 ml(RTU)
  • CM208-0.1ml
    0.1 ml(RTU)
  • CM208-0.5ml
    0.5 ml(RTU)
  • HAM208-3ml
    3 ml(RTU)
  • HAM208-6ml
    6 ml(RTU)