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Colon Ca stained with anti-CA19.9

CA 19.9-121SLE

CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis a and/or Lewis b blood group antigens. In normal tissues, sialyl Lewis a antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings.

Specifications

  • Source
    Mouse Monoclonal
  • Clone
    121SLE
  • Class
    IVD
  • Isotype
    Mouse IgM, kappa
  • Tested Reactivity
    Human,FFPE
  • Localization
    Cytoplasm
  • Positive Control
    Colon Ca, Stomach

Ordering Information

  • Catalog
    Pack Size
  • PM206-3ml
    3 ml(RTU)
  • PM206-6ml
    6 ml(RTU)
  • CM206-0.1ml
    0.1 ml(Conc.)
  • CM206-0.5ml
    0.5 ml(Conc.)
  • HAM206-3ml
    3 ml(RTU)
  • HAM206-6ml
    6 ml(RTU)