Close
Breast Ca stained with anti-Progesterone Receptor

Progesterone Receptor-EP2

The human progesterone receptor (PR), is a ligand-activated transcription factor and is a member of the steroid receptor family. PR exists in humans as two isoforms; PR-A (94 kDa) which lacks the first 164 amino acids of PR-B and PR-B (114 kDa). While the two forms of PR have similar DNA- and ligand-binding affinities they have opposite transcriptional activities. PR-B functions as an activator of progesterone-responsive genes, while PR-A functions as a strong transdominant repressor of PR-B. This anti-PR recognize both PR-A and B. It labels epithelial cells of breast, ovary and endometrium.

Specifications

  • Source
    Rabbit Monoclonal
  • Clone
    EP2
  • Class
    IVD
  • Isotype
    Rabbit IgG
  • Tested Reactivity
    Human,FFPE
  • Localization
    Nucleus
  • Positive Control
    Breast cancer

Ordering Information

  • Catalog
    Pack Size
  • PR068-3ml
    3 ml(RTU)
  • PR068-6ml
    6 ml(RTU)
  • CR068-0.1ml
    0.1 ml(Conc.)
  • CR068-0.5ml
    0.5 ml(Conc.)
  • HAR068-3ml
    3 ml(RTU)
  • HAR068-6ml
    6 ml(RTU)