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Ovarian Ca stained with p53

p53-BP-53-12

p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair.p53 is overexpressed in over 50% of human cancers. Positive staining of p53 detected by immunohistochemistry has been observed in colon cancer, breast cancer and ovary cancer.

Specifications

  • Source
    Mouse Monoclonal
  • Clone
    BP-53-12
  • Class
    IVD
  • Isotype
    Mouse IgG2a
  • Tested Reactivity
    Human, FFPE
  • Localization
    Nucleus
  • Positive Control
    Ovarian Ca, Breast Ca, Colon Ca

Ordering Information

  • Catalog
    Pack Size
  • PM101-3ml
    3 ml(RTU)
  • PM101-6ml
    6 ml(RTU)
  • CM101-0.1ml
    0.1 ml(Conc.)
  • CM101-0.5ml
    0.5 ml(Conc.)
  • HAM101-3ml
    3 ml(RTU)
  • HAM101-6ml
    6 ml(RTU)